KLIOGEST N Filmtabletten 28 St (estradiol-2mg/norethisterone-1mg/norethisterone-0.88mg)

The drug is a continuous combined hormone replacement therapy (HRT) medication that is taken daily without interruption. The medicine is suitable for women whose last menstruation was at least 1 year ago.
The tablets contain 2 hormones: 2 mg of estradiol (an estrogen identical to estradiol produced in the ovaries) and 1 mg of norethisterone acetate (a progestin that acts similarly to the body’s own progesterone (luteal hormone).
The medicine is applied.
to relieve symptoms after menopause
During menopause, a woman’s production of her own estrogen decreases. This can cause symptoms such as hot flashes in the face, neck, and chest (called hot flashes). The drug relieves these symptoms that occur after menopause. You will only be prescribed medication if your symptoms significantly affect your daily life.
to prevent osteoporosis (bone loss)
Some women develop brittle bones (osteoporosis) after their last period. You should discuss all available treatment options with your doctor.
If you are at high risk of bone fractures due to osteoporosis and cannot tolerate or cannot use other drugs used for this purpose, you can use the drug to prevent osteoporosis after menopause.
The medicine is used in women who still have a uterus and whose menopause (last menstruation) occurred more than 1 year ago.
Experience in treating women over 65 years of age is limited.
The medicine cannot be taken
if any of the following situations apply to you. If you are unsure about any of the points below, talk to your doctor before you start taking the product.
Do not start taking the drug:
if you have or have had breast cancer or are suspected of having it
if you have or have had cancer of the lining of the uterus (endometrial cancer) or are suspected of having such an estrogen-dependent cancer
if you have vaginal bleeding for which your doctor has not determined the cause
if you have endometrial hyperplasia (excessive thickening of the lining of the uterus) that cannot be treated
if you have or have had a blood clot in your veins (venous thromboembolism), legs (deep vein thrombosis) or lungs (pulmonary embolism).
if you have a bleeding disorder (thrombophilia, such as protein C deficiency, protein S deficiency or antithrombin deficiency).
if you have or have had a condition caused by a blood clot in your arteries, such as a heart attack, stroke or angina, which is characterized by chest discomfort, pressure or pain
if you have or have had liver disease and your liver function tests have not returned to normal
if you have a rare hereditary disease, porphyria (a metabolic disease that affects the formation of blood pigments)
if you are allergic (hypersensitive) to estradiol, norethisterone acetate or any of the other ingredients of this medicine.
If any of the above occur for the first time while taking the medicine, stop taking it immediately and contact your doctor immediately.